BioTechniques for Preclinical Development
May 2009 | Vol. 46 | No. 6
May 2009 | Vol. 46 | No. 6
Volume:46
, Issue Number:6
Cover Image:
Bone scan of a normal living mouse measured using the Maestro (CRI, Inc.),
a whole body fluorescence imager enabling spectral unmixing of fluorescent
signals. Bony elements (green) are visualized with the near-infrared
fluorescent probe Osteosense-680 (VisEn Medical). Kidneys (red) are
visualized using another near-infrared fluorescent probe (emitting at 800
nm) that accumulates in the kidneys. Autofluorescence of food in the
intestine is seen in blue. Colors are false colors of the unmixed signals.
Image courtesy of Clemens W.G.M. Löwik, Eric L. Kaijzel, and Ivo Que, Leiden
University Medical Center, Leiden, The Netherlands.
Research Reports
James M. Dixon,
Mariusz Lubomirski,
Dhammika Amaratunga,
Tom B. Morrison,
Colin J.H. Brenan,
and Sergey E. Ilyin
BioTechniques, Vol. 46, No. 6, May 2009, pp. ii–viii
doi
10.2144/000112838
Benchmarks
Uwe Riek,
Sacnicte Ramirez,
Theo Wallimann,
Uwe Schlattner
BioTechniques, Vol. 46, No. 6, May 2009, pp. ix–xii
doi
10.2144/000113130