FluxOR™, a Universal Potassium Channel Assay Screening BacMam Delivered and Stably Expressed Targets
Potassium ion channels are important targets in drug discovery and safety testing for which current assays suffer expense, low throughput or lack of proximity to the target. A robust and homogenous assay that allows for functional HTS measurements of potassium channel activity would give the screening community a useful tool for the interrogation of potassium channels in compound library screening.
Misidentification as well as inter- and intra-species cross contamination of cell lines is widespread and has a substantial negative impact on biomedical research. In this study, an approach used by RADIL for analyzing human and rodent cell lines for inter and intra--species contamination followed by authentication of cell line identity is described.