Microscope-based, high content instruments are used for many cell based assays in high content screening (HCS). For efficient and rapid analysis most assays require the use of higher resolutions which entail lengthy read times, using single colours.
A large percentage of drugs fail in clinical studies,or are withdrawn from the market due to hepatic toxicity. Therefore, highly predictive in vitro assays suitable for safety and efficacy testing are extremely important for improving the drug development process and reducing drug attrition.
Salmonella infections are among the leading bacterial cause of illness in the United States, with poultry being a major global reservoir of Salmonella. Because of health concerns and the cost burden associated with Salmonella infections, regulations require reporting of Salmonella serotypes for detected cases.
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