Please select the year of publication for the sector category you
wish to view.
David S. Baskin, Marsha A. Widmayer, Martyn A. Sharpe
Here we describe the substitution of fluorescently labeled ddUTP for dUTP in the TUNEL assay to allow quantification of generated fluorescence signals by epifluorescence microscopy. The capping of...
1 ), blogs and news outlets alike were buzzing about this new form of “synthetic life.” The media furor that resulted quickly incited questions about the future of synthetic biology, its moral...
Sarah A. Webb
Shuffling cards
In the late 1990s, the development of soft lithography methods using polydimethylsiloxane (PDMS) by George Whitesides' group at Harvard University and others brought microfluidics...
Patrick C.H. Lo, Kristie Nybo
Certain recombinant fusion proteins require short peptide linkers between protein domains to provide flexibility or increase stability during synthesis. For some fusion proteins, however, the...
Nijsje Dorman, Patrick C.H. Lo, Kristie Nybo
Small fluorescent labels such as the fluorescein arsenical hairpin binder (FlAsH) make popular alternatives to bulky fluorescent proteins. FlAsH, along with its color variant ReAsH (red arsenical...
Andrea Zanardi, Dario Bandiera, Francesco Bertolini, Chiara Corsini, Giuliana Gregato, Paolo Milani, Emanuele Barborini, Roberta Carbone
Fluorescence in situ hybridization (FISH) represents a major step in the analysis of chromosomal aberrations in cancer. It allows the precise detection of specific rearrangements, both for diagnostic...
Kristie Nybo
This month's question from the Molecular Biology Forums (online at
Andrew S. Dixon, Carol S. Lim
Protein interactions are critical for normal biological processes and molecular pathogenesis. While it is important to study these interactions, there are limited assays that are performed inside the...
Xiaoying Chen, Yun Bai, Jennica L. Zaro, Wei-Chiang Shen
In order to achieve optimal biological activity and desired pharmacokinetic profiles, a dithiocyclopeptide linker was designed for in vivo release of protein domains from a recombinant fusion...
Kristie Nybo
Jeff Lichtman's research on neuronal development and his role in creating the Brainbow mouse caught our attention