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In some PCR reactions, primers containing portions noncomplementary to the target region (referred to as flaps) are commonly used to add a utility sequence, such as a restriction or universal...
Lise Lotte Hansen, Bo Eskerod Madsen, Kristina Pedersen, Carsten Wiuf
Single nucleotide polymorphisms (SNPs) are highly abundant in the genome and especially useful in the search for disease susceptibility genes via population-based association or linkage studies....
Luis G. Acevedo, A. Leonardo Iniguez, Heather L. Holster, Xinmin Zhang, Roland Green, Peggy J. Farnham
The technique of chromatin immunoprecipitation (ChIP) is a powerful method for identifying in vivo DNA binding sites of transcription factors and for studying chromatin modifications. Unfortunately,...
Manfred Kayser
Bi-parentally inherited short tandem repeat polymorphisms have been routinely used in human identity testing for about 25 years. More recently, the analysis of uni-parentally inherited markers from...
