to BioTechniques free email alert service to receive content updates.
Molecular Biology
Cancer Gene Panels
Life Technologies has developed the Ion AmpliSeq BRCA1 and BRCA2 Panel design .
The BRCA panel analyzes the coding regions of the tumor suppressor genes BRCA1 and BRCA2, which have been implicated in hereditary breast and ovarian cancers. The colon and lung panel analyzes more than 500 mutations in 22 associated genes, using the power and simplicity of the established Ion AmpliSeq technology. Significant and ongoing improvements with Ion sequencing have enabled these Ion AmpliSeq panels to accurately call all variants of interest, including those within difficult sequence contexts.