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DNA Methylation Target-Enrichment System
Agilent Technologies’ SureSelect XT Human Methyl-Seq target-enrichment system is designed for epigenetic research into DNA methylation sites.
The assay combines the company’s SureSelect target-enrichment platform with bisulfite sequencing, the standard for DNA methylation research and the first comprehensive discovery system. This enables sequence coverage of only the most relevant regions for epigenetic studies, including those associated with a wide range of disorders. The system allows researchers to analyze over 3.7 million individual CpG dinucleotide sequences for their methylation state. The system targets promoters, canonical CpG islands, and the more recently described "shores" and "shelves" found up to 4 kilobase pairs on either side of CpG islands.
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Agilent Technologies is the world’s premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis. Agilent has two primary business segments: Bio-Analytical Measurement and Electronic Measurement. The company has 19,600 employees and serves customers in more than 110 countries. Agilent had revenue of $5.8B in fiscal year 2008.