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Molecular Biology
Digital PCR System
RainDance Technologies RainDrop digital PCR system is designed for sensitivity, multiplexing, and absolute quantitation in PCR analysis.
Capable of generating more than a billion reactions in a single day, the
system transforms the performance of molecular assays by enabling digital
answers across a number of important applications including low-frequency
tumor allele detection, gene expression, copy number variation, and SNP
measurement.
Built on the company's RainStorm picodroplet technology, the system generates
up to 10 million picoliter-sized droplets per lane. Since each droplet
encapsulates a single molecule, researchers can quickly determine the
absolute number of droplets containing specific target DNA and compare that
to the number of droplets with background wild-type DNA. The system also
shifts the current digital PCR (dPCR) paradigm from a
single-color-per-marker approach to a two color and varying probe intensity
method that is capable of multiplexing up to 10 markers.
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