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Fluorescence In Situ Hybridization (FISH), Fluorescence Microscopy, Imaging
GFP-Booster for bioimaging
ChromoTek's bioimaging tool GFP-Booster is designed to restore or increase the green fluorescent protein (GFP) signal in super-resolution microscopy.
The photo stability and the quantum efficiency of GFP are not sufficient for super-resolution microscopy (3-D-SIM or STED) of fixed samples from cells expressing GFP fusion proteins to visualize specific structures. Furthermore, many currently used procedures for FISH or BrdU detection lead to disruption of the GFP signal. GFP Booster consists of a chemical fluorescent dye that is covalently attached to a GFP Nanotrap providing high fluorescence intensities and signal-to-noise ratios.
 
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ChromoTek is a biotech company specialising in molecular tools for bioimaging and proteome analysis. ChromoTek’s lead product, the GFP-Trap®, is used for immunoprecipitation (IP, coIP) and/or affinity purification of GFP-tagged proteins. The company also develops vectors and cell lines for high content analysis (HCA) of important cellular markers, with a primary focus on cell cycle, apoptosis and metabolism.

ChromoTek was founded in 2008 and is located in Martinsried, Germany. The company works closely together with the Center for Integrated Protein Science Munich at the Biocenter of the Ludwig-Maximilian-University Munich. ChromoTek currently markets its products in four continents (Europe, North America, Asia and Australia).