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Cell Biology, Molecular Biology
Label-free Interaction System
NanoTemper's Monolith NTLabelFree instrument is designed for interaction studies in free solution without the need for a fluorescent label.
The system complements the company's existing instrument from the monolith series: Monolith NT.115, which allows measurement of binding events between biomoelcules by adding a fluorescent label to one of the molecules involved. The label-free system extends the application to systems that are difficult to label fluorescently. The system combines the advantages of measuring as close as possible to native conditions with the well known advantages of MST as low sample consumption, fast measurement speed, and straight forward handling. The application range includes interaction of membrane receptors, soluble proteins, peptides, nucleic acids, sugars, small molecules as well as macromolecular complexes.
 
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