DNAStar's Lasergene 9.1 software upgrade includes support for genome-wide association studies (GWAS) using next-generation DNA sequence information.
The software also integrates protein sequence, structure, and bioinformatic
method capabilities in one application. The GWAS functionality builds on a
wide variety of tools already available in the software, bringing them
together in one workflow to support analysis of one sample, all samples, or
any subset when working with multi-sample sequencing data. SNPs can be
assessed individually or in groups in the new software and a unique SNP
scoring method is being introduced to indicate the relative importance of
various SNPs within a given context. With the update, the software's macromolecular
sequence and structure viewer now provides bioinformatic analysis of
proteins as well. the update also supports the identification of DNA
sequence structural variants and expands the database information available
to users to include both dbSNP and COSMIC data for many organisms.