Cytoo's Motility plates are specifically designed to study cell migration for screening applications in oncology and drug discovery, showing characteristics closer to those found in vivo.
The product is based on the company's 2D+ cell culture platform of 24- and
96-well plates that employ standard and custom adhesive micropatterns to
guide cell architecture and behavior in culture. By defining the 2D topology
of cell adhesion, the 2D+ cell culture platform enables fine control of the
spreading and 3D shape of cultured cells in single- or multi-cellular
configurations. This approach results in control of cell contractility,
cell polarity, organelle positioning, and cell division axis. This
technology addresses a major concern with traditional 2D culture, in which
cells spread and move in an uncontrolled manner, introducing a considerable
but unnoticed variability in cell function.