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Cell-Signaling Assays, Phosphorylation Analysis/Kinase Assays
Nunc Edge plates
The flatness of the Edge Plates eliminates the occurrence of chromatic aberrations
Thermo Fisher Scientific announced the Thermo Scientific Nunc Edge 96-well Plates for cell-based assays. The new Nunc Edge plates incorporate large perimeter evaporative buffer zones that eliminate well-to-well variability, while dramatically reducing the overall plate evaporation rate to <2 percent after 7 days of incubation. As a result, more viable and healthy cell yields are obtained. These zones enable the use of all 96 wells, greatly reducing the edge effect commonly experienced in cell culture, while maintaining data consistency throughout the plate. A minimal volume loss of 10 percent can concentrate media components and metabolites enough to alter cell physiology, a phenomena which is more pronounced in the outer and corner wells. The Nunc Edge plates significantly reduce its occurrence, effectively maintaining sample concentrations over long periods of incubation. The prevention of cell death and toxicity in the plates’ outer wells allows results to remain more true to the population phenotype for more efficient, high throughput analysis. For high content analysis applications, the Nunc Edge plates offer outstanding flatness and superior image quality. In cell-based assays where multiple targets are simultaneously imaged, all the fluorescence from a single location needs to focus at the same point within the imaging system. The flatness of the Edge Plates eliminates the occurrence of chromatic aberrations, enabling efficient automated imaging. Furthermore, varying reagent concentrations from assay washing/aspiration steps are also dramatically reduced.
 
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About Thermo Fisher Scientific, Inc.

Thermo Fisher Scientific Inc. is the world leader in serving science, enabling customers to make the world healthier, cleaner and safer. With 2008 revenues of $10.5 billion, the company has approximately 34,000 employees and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings.

Serving customers through two premier brands, Thermo Scientific and Fisher Scientific, the company helps solve analytical challenges from routine testing to complex research and discovery.

The Thermo Scientific brand represents a complete range of high-end analytical instruments as well as laboratory equipment, software, services, consumables, and reagents to enable integrated laboratory workflow solutions.

Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education.

Together, the company offers the most convenient purchasing options to customers and continuously advance our technologies to accelerate the pace of scientific discovery, enhance value for customers and fuel growth for shareholders and employees alike.

Contact information

Thermo Fisher Scientific, Inc.
81 Wyman Street
Waltham, MA 02454 USA
Tel: +1 781-622-1000
Fax: +1 781-622-1207






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