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Polyhistidine-tagged Protein Analysis Chip
Bio-Rad Laboratories’ ProteOn HTE Sensor Chip is designed to provide a robust solution for pharmaceutical researchers studying the interaction of polyhistidine-tagged protein with small molecule drugs using surface plasmon resonance.
The chip’s tris-NTA coated surface uses three NTA molecules instead of the traditional monomer version of the molecule. Tris-NTA yields a stronger binding interaction with the target, resulting in improved data quality compared to other biosensor solutions for capturing polyhistidine-tagged targets. Other available options may result in the protein complex leaching off the surface, rendering the surface unsuitable for reuse. And data analysis may require intensive software corrections.
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Bio-Rad Laboratories is a corporation providing a broad range of innovative tools and services to the life science research and clinical diagnostics markets. Founded in 1952, Bio-Rad has a global team of more than 6,500 employees and serves more than 85,000 research and industry customers worldwide through its global network of operations. Throughout its existence, Bio-Rad has built strong customer relationships that advance scientific research and development efforts and support the introduction of new technology used in the growing fields of genomics, proteomics, drug discovery, food safety, medical diagnostics, and more.