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Molecular Biology
Primers for Cancer Mutation Detection
Swift Biosciences’ myT Primer reagents are designed for the detection of key cancer mutations. myT BRAF-Ultra, an ultrasensitive version of myT BRAF, provides 0.01% sensitivity down to single-copy detection of BRAF mutations.
The primer can detect less than 10 copies of mutant BRAF V600E/K with very low breakthrough amplification from a background of 10,000 wild-type genomic DNA copies. While the primer works well with fresh frozen and FFPE samples, this level of sensitivity also makes the product useful when the sample material is limiting or where the target is present at very low concentration.
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