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Molecular Biology
nCounter miRGE Assay for miRNA Profiling
NanoString Technologies' nCounter miRGE Assay is designed to enable researchers to investigate expression levels of both micro RNAs (miRNAs) and the messenger RNAs (mRNAs) they potentially regulate in a single reaction, without the need for amplification.
The miRGE Assay provides the capacity to perform multiplexed profiling of 5-30 miRNAs and 100-200 mRNAs simultaneously, with specificity and sensitivity comparable to qPCR. Like all nCounter assays, the kit is compatible with multiple sample types, including FFPE samples. The assay is available for human, mouse and rat samples. The nCounter Analysis System is a fully automated digital detection and counting system with a simple workflow. The assays contain all of the reagents and consumables required to conduct an experiment. Minimal sample input requirements and compatibility with a variety of sample types, extends the utility of the platform. In addition to miRNA assays, NanoString provides assays for copy number variation and gene expression analysis. The nCounter Analysis System is currently available for research use only.
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NanoString Technologies is a privately held provider of life science tools for translational research and developer of molecular diagnostics. The company’s nCounter® Analysis System is the first and only technology platform to deliver highly multiplexed, direct profiling of individual molecules in a single reaction without amplification. The nCounter Analysis System offers a cost-effective way to easily profile hundreds of gene transcripts, copy number variations, or miRNAs simultaneously with high sensitivity and precision. The company’s technology enables a wide variety of basic research and translational medicine applications, including biomarker discovery and validation. NanoString is also developing the technology for use in molecular diagnostics.