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Using CRISPR/Cas9 to Understand Transcription and Control Gene Expression

October 8, 2014
1 PM EDT / 10 AM PDT / 6 PM BST

A FREE Web Event - Registration Open Now
www.biotechniques.com/CRISPR

CRISPR/Cas9 presents a new way for researchers to explore how gene expression is controlled and regulated in cells. Although we know much about this process, recent discoveries (new RNAs, alternative splicing events) make it clear that there is much more to be learned about how genomes encode biological information.

This webinar features:

• The latest advances in CRISPR/Cas9 technology and how these advances are being applied in clever and creative ways to explore genome function

• A discussion of best practices for CRISPR/Cas9 targeting and design

• A live question and answer session

Speakers:

Timothy K Lu - Dept. of Biological Engineering, MIT

Evan Whitehead - Dept. of Cellular and Molecular Pharmacology, UCSF Center for Systems and Synthetic Biology

Moderator:

Patrick C.H. Lo, Ph.D. - Senior Editor, BioTechniques

Sponsored by:

A FREE Web Event - Registration Open Now
www.biotechniques.com/CRISPR

Video Date: October 08 2014 Run Time:

Exploring Neurons and Synapses: Imaging Tools and Techniques
Online Event

Tuesday, September 16, 2014
1 PM EDT / 10 AM PDT / 6 PM BST

A FREE Web Event - Registration Open Now
www.biotechniques.com/synapses

In the coming years, considerable effort and resources will be directed at understanding the neural connections of the brain.

This webinar examines many of the tools being used to study how neurons interact with one another at their synapses.

This event will provide both experienced and novice researchers with an excellent overview of the current optical imaging methods driving neuroscience today.


This webinar features:

• An introduction to STED super-resolution imaging technology

• The application of STED imaging and other techniques for studying the overall organization of the synaptic bouton and for analyzing synaptic vesicle recycling and the localization of synaptic proteins

• A description of how STED microscopy has helped to refine our understanding of the morphological and functional dynamics of synapses in living specimens

• A live question and answer session

Speakers:

Silvio Rizzoli - Department of Neuro- and Sensory Physiology, European Neuroscience Institute, University of Göttingen Medical Center

Valentin Nagerl - Interdisciplinary Institute for Neuroscience (IINS), University of Bordeaux

Moderator:

Patrick C.H. Lo, Ph.D. - Senior Editor, BioTechniques

Sponsored by:

A FREE Web Event - Registration Open Now
www.biotechniques.com/synapses

Digital Pathology: Expanding the Microscope Slide Box

Digital Pathology: Expanding the Microscope Slide Box

A Free Web Event
Available On Demand Now

Understanding human disease progression at the cellular level often requires examination of tissue sections on slides. With its ability to generate and store images of microscope slides and thereby allow scientists to examine specific anatomical locations and landmarks quickly and efficiently, digital pathology has made tremendous inroads in both academic and clinical laboratory settings. In this special webinar, attendees will have a unique opportunity to learn more about: (i) digital pathology applications, (ii) instrumentation and technology (both in a low-throughput and high-throughput format), and (iii) analysis tools and data storage solutions. Be a part of this special web event, and learn more about how digital pathology is enabling students, research scientists, and clinical pathologists gain a more comprehensive understanding of anatomical pathology and human disease.

Attendees will:

  • Learn about the implementation of digital pathology workflows in academic and clinical settings
  • Hear about the latest approaches in digital pathology image analysis
  • Find out about the challenges of data storage and security when establishing a digital pathology workflow
  • Be able to ask questions to a panel of experts

Moderator:

Patrick C.H. Lo, Ph.D.
Associate Editor, BioTechniques

Speakers:

John Vallone, M.D., Ph.D.
Associate Professor of Clinical Medicine, Keck School of Medicine, University of Southern California

Cynthia Loomis, M.D., Ph.D.
Director, Experimental Pathology Shared Resource, NYU School of Medicine

Sponsored by:

A Free Web Event
Available On Demand Now


Confocal and Two-photon Microscopy Methods for Imaging the Brain

Confocal and Two-photon Microscopy Methods for Imaging the Brain


A FREE Web Event



Available Now On Demand

A deeper understanding of brain function requires visualization of the complex architecture of neurons and their connections. With the ability to peer deeper into samples than conventional light microscopy approaches, confocal and two-photon microscopy are proving to be indispensable tools for such brain mapping studies. In this special webinar, two researchers working at the cutting-edge of brain imaging will discuss their applications of the latest confocal and two-photon microscopy techniques. From fluorescent labeling and imaging of neural circuits using the Brainbow system to in vivo imaging of brain structure, function, and blood flow, this webinar will give researchers a deeper appreciation of the potential for new microscopy methods to unlock the secrets of the cellular world. Unique insights into sample handling and processing of multicolor images will also be presented, and attendees will have the opportunity to ask questions.

Moderator:

Patrick C.H. Lo, Ph.D.
Senior Editor, BioTechniques

Speakers:

Dawen Cai, Ph.D.
Assistant Research Scientist, Department of Physics,
University of Michigan

Ian R. Winship, Ph.D.
Assistant Professor, Neurochemical Research Unit,
Department of Psychiatry,
University of Alberta

Sponsored by:

A Free Web Event

www.biotechniques.com/microscopy

Workshop on Recent Advances and Applications of Laser Capture Microdissection
Virtual Event

Workshop on Recent Advances and Applications of Laser Capture Microdissection

A Free Web Event
Available on Demand Now

Since its introduction in 1996, laser capture microdissection (LCM) has emerged as an important technique for isolation of specific subsets of cells from complex tissues or other biological samples. Cellular material isolated by LCM is often used in downstream applications including PCR, microarray analysis, and sequencing. Several recent advances in LCM approaches have enhanced and expanded the range of these applications even further. In this web-based workshop, an overview of LCM will be provided along with descriptions and discussions of several recent LCM technology advances.

Attendees will:

  • Learn about the development and evolution of LCM approaches, including common applications and troubleshooting tips
  • Gain valuable insights into new developments in LCM technology, including the development of expression microdissection techniques
  • Engage in a discussion/question and answer session with a panel of LCM experts

Moderator:

Patrick C.H. Lo, Ph.D.
Associate Editor, BioTechniques

Speakers:

Robert Bonner, Ph.D.
Head, Section of Medical Biophysics. National Institute of Child Health and Human Development, National Institutes of Health

Michael Tangrea, Ph.D.
Staff Scientist, Pathogenetics Unit. National Cancer Institute, National Institutes of Health

Jason Hipp, MD., Ph.D.
Rabson fellow, Laboratory of Pathology, National Cancer Institute, National Institutes of Health

Sponsored by:

A Free Web Event
Available on Demand Now