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Revolutionary Techniques

07/01/2013
Andrew S. Wiecek

To celebrate the Fourth of July holiday this week, we take a look at three revolutionary techniques that have changed how molecular biology gets done in the lab.


Laboratory techniques are constantly evolving. New methods and protocols are constantly attempting to overthrow less efficient techniques and to gain some representation among the citations. And like the American Revolution, we have our founding fathers too: Linus Pauling, Sydney Brenner, Kary Mullis, and Frederick Sanger, just to name a few.

New methods and protocols are constantly attempting to overthrow less efficient techniques and to gain some representation.




So as we get ready to celebrate Independence Day this week, we take a look at some of the revolutionary techniques in molecular biology.

PCR: A Revolutionary Technique

“Making it Real” Time

Kent E. Vrana

It has been 30 years since the first description of the polymerase chain reaction (PCR)—corresponding, coincidentally, with the year of the first issue of BioTechniques. Ensuing decades have seen remarkable advances in this revolutionary technique. Read more...

Genome Editing Revolution

Genome Editing Revolution, Benchtalk, Episode 3

In this episode of our podcast, researchers Keith Joung and A. Francis Stewart join host Andrew S. Wiecek to discuss the revolution in gene editing techniques. Also, our roundtable with science writers Sarah C.P. Williams and Ashley Yeager. Read more...

Revolutionary Changes in RNA Analysis

Examining Molecular Biology in Humans

Alex Parker, Ian McCaffery, and Scott D. Patterson

The analyses of RNA, including splice-variants, and sub-cellular and serum/plasma-based proteomics, are undergoing revolutionary changes that will enable extensive, quantitative characterization of much of the molecular activity within a cell. Read more...