BioTechniques Protocol Guide 2008
EpiTYPER is a tool for the discovery and quantitative analysis of DNA methylation that uses base specific cleavage and matrix-assisted later desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Using the speed and accuracy of the MassARRAY® system, this method is ideal for discovery of methylation, for discrimination between methylated and non-methylated samples, and for quantifying the methylation levels of DNA.
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