During the development and optimization of antibody reagents for therapeutics, the key is to identify and characterize antibodies with very high affinity and specificity for the intended target, as well as those with low cross-reactivity. The use of fragment antigen binding (Fab) phage display libraries for panning potential Fab candidates, though powerful, is both time-consuming and costly.
BioTechniques Protocol Guide 2008
Label-free interaction analysis is used extensively throughout academic research and in the pharmaceutical and biotechnology industries, playing a vital role throughout life science research, as well as LMW drug discovery, biopharmaceutical development and clinical immunogenicity studies as well as manufacturing and QC. Comprehensive characterization of molecular interactions must include high quality information on parameters such as binding specificity, affinity (the strength of the interaction) and kinetics (the rates at which the interactants bind and dissociate).
Monoclonal antibodies are of particular interest in basic biomedical research and for the diagnosis and treatment of various diseases. Screening, profiling, and production of antibodies involve tedious and time-consuming procedures.
Label-free protein interaction analysis is used extensively throughout academic research and in the pharmaceutical and biotechnology industries, playing a vital role in proteomic studies, small molecule drug discovery, biopharmaceutical development and clinical immunogenicity studies as well as manufacturing and QC.Comprehensive characterization of how proteins interact with other molecules must include high quality information on parameters such as binding specificity, affinity (the strength of..
rightcontent.jsp called otherwise condition
BioTechniques is always looking for author-submitted protocols related to peer-reviewed papers, so submit your protocols today to our editorial team. Suppliers or advertisers interested in publishing their protocols should also submit.
Click here for more information
In order to deliver a personalised, responsive service and to improve the site, we remember and store information about how you use it. This is done using simple text files called cookies which sit on your computer.