Vendor-submitted protocol.
Published in
November
2009
During the development and optimization of antibody reagents for therapeutics, the key is to identify and characterize antibodies with very high affinity and specificity for the intended target, as well as those with low cross-reactivity. The use of fragment antigen binding (Fab) phage display libraries for panning potential Fab candidates, though powerful, is both time-consuming and costly.
Vendor-submitted protocol.
Sponsored by
Bio-Rad Laboratories
Published in
BioTechniques Protocol Guide 2008
Monoclonal antibodies are of particular interest in basic biomedical research and for the diagnosis and treatment of various diseases. Screening, profiling, and production of antibodies involve tedious and time-consuming procedures.