How New Technology and Methods Are Changing Our Understanding
Featuring:
Session Descriptions
Session 1: Accelerating Genome Discovery through the Use of Next-Generation Sequencing
This session will provide participants with a better understanding of the multiple uses of next-generation Sequencing when it comes to understanding gene structure and organization as well as the roles that RNA can play in regulating gene expression.
Keynote Address:
Jay Shendure, Associate Professor, University of Washington
Dr. Shendure will present an overview on next-generation sequencing applications in human genetics.
Session Speakers:
Ira Hall, Assistant Professor, University of Virginia
Dr. Hall will discuss his recent work using next-generation sequencing to decipher and understand copy number variations.
Srikumar Sengupta, Assistant Scientist, Morgridge Institute for Research
Dr. Sengupta will describe how RNA-seq approaches are being applied to understand transcription regulation in a variety of cell types.
Session 2: Understanding the Role of Epigenetic Change in Gene Regulation
This session examines the impact of histone/protein modifications and DNA methylation patterns on gene expression as well as the roles epigenetic modifications play in stem cell and cancer biology.
Keynote Address:
Brian Strahl, Associate Professor, University of North Carolina, Chapel Hill
Dr. Strahl will present an overview of the latest research on histone modifications and the role these modifications play in gene regulation, placing this work in context with other recent advances in the field of epigenetics. Sponsored by PerkinElmer.
Session Speakers:
Mitchell Guttman, Postdoctoral Fellow, Eric Lander Lab, MIT and Broad Institute, Cambridge, Massachusetts
Dr. Guttman will discuss recent findings on the roles large non-coding RNAs play in the regulation of gene expression and chromatin structure.
Donncha Dunican, Investigator Scientist, MRC Human Genetics Unit, Edinburgh, U
Dr. Dunican will discuss new approaches being used for the study of global DNA methylation patterns, chromatin structure, and gene regulation.
Session 3: Recent Advances in Proteomic
This session will discuss the tools currently driving the field of proteomics, including antibody generation technologies, mass spectrometry analysis of proteins and their modifications, and assays to examine how proteins interact in vivo.
Keynote Address:
Joshua J. Coon, Associate Professor, University of Wisconsin, Madison
Dr. Coon will provide an overview on quantitative proteomics and the use of mass spectrometry in protein analysis.
Session Speaker:
David Rimm, Professor, Yale University
Dr. Rimm will discuss recent advances in antibody generation technologies and antibody validation, as well as their impact on techniques such as immunohistochemistry. sponsored by R&D Systems.
Session 4: Frontiers in Cell Analysis
This session will examine the latest approaches for analysis of cell structures and cell identification, as well as tools that enable the study of how cells interact with their extracellular environments.
Keynote Address:
John Masters, Professor, University College, London
Dr. Masters will present an overview on the challenges associated with cell line authentication and describe the latest techniques and methods being used to curb the problem of non-authenticated cell lines in basic research. Sponsored by ATCC.
Session Speakers:
Lonnie Shea, Professor, Northwestern University
Dr. Shea will discuss the latest advances in three-dimensional cell culture methodologies and the possible applications of these approaches in tissue engineering. Sponsored by Mirus Bio.
Mark Siegal, Associate Professor, New York University
Dr. Siegal will discuss cellular signaling networks and recent work his group has performed using live-cell imaging to look at variation in growth strategies in yeast.
Each session includes a live Q&A session


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