A window to cancer’s soul: the creation of intravital microscopy and the rise of the TME

Rakesh Jain (left) is the Andrew Werk Cook Professor of Radiation Oncology at Harvard Medical School (MA, USA) and the Director of the Edwin L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital. Throughout his career, Rakesh has innovated new techniques and approaches to interrogate the abnormal tumor microenvironment (TME) and find ways to ‘normalize’ it to improve the deliverability and impact of cancer therapeutics. At this year’s meeting of the American Association of Cancer Research (AACR; 25-30 April; Chicago, IL, USA) Rakesh won the AACR Award for Lifetime Achievement in Cancer Research for his foundational and ongoing work...