How is the integration of CRISPR and 3D culture systems advancing disease modeling and personalized medicine? – Find out in your latest issue of BioTechniques!

In this issue of BioTechniques, we present a colorimetric-based method for quantifying biotin binding capacity, the development of a portable device for RNA extraction and a protocol for assessing cell-line immortality.
Technology News
CRISPR in 3D: innovations in disease modeling and personalized medicine
Editorial
Importance of a reference ladder in analytical testing of CRISPR HDR donor ssDNA templates
Reports
A single-cell 3D dynamic volume control system for chondrocytes
Development and validation of a portable device for lab-free versatile nucleic acid extraction
Benchmark
Optimized for routine: highly sensitive fluorescent Telomeric Repeat Amplification Protocol (f-TRAP)
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