Single-cell sequencing provides new wisdom about our teeth

A new single-cell sequencing atlas of human teeth has provided a comprehensive understanding of their make up, and could take us one step further toward a reality of regenerative dental treatments. Teeth are a unique tissue, unique to each person. Underneath your enamel lies dentin and the dental pulp, a vascularized and innervated tissue lined by odontoblasts. The tooth is then anchored to the bone via the periodontium, which is crucial for tooth stability. Both the pulp and the periodontium are subject to pathologies such as caries and periodontitis, which can often result in the need for dental treatments. However,...