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How effective is a COVID-19 booster vaccine?

Written by Storm Johnson (Commissioning Editor)

The largest real-world observational study of the third ‘booster’ dose of the mRNA COVID-19 vaccine demonstrates its effectiveness against severe SARS-CoV-2-related illness, hospitalization, and death.

A collaboration of researchers from Clalit Research Institute (Ramat Gan, Israel) and Harvard Medical School (MA, USA) conducted the largest real-world study assessing the effectiveness of a third ‘booster’ dose of mRNA vaccine against severe SARS-CoV-2 Delta variant infection. Analyzing data from Israel’s health record databases, the findings demonstrated that receiving the third dose of Pfizer/BioNTech BNT162b2 vaccine is indeed effective in protecting against severe COVID-19 infection outcomes, compared to receiving only two doses.

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