Cas9 goes into stealth-mode

A new method has set out to tackle one of the limitations of CRISPR, promising to make gene-editing with CRISPR-Cas9 more reliable and “stealthy”. CRISPR techniques for gene editing have been labeled a scientific breakthrough and opened up a whole new world for research; however, they have been dogged by problems. While CRISPR techniques could help treat genetic diseases and transform ecosystems, potential limitations of CRISPR such as off-target effects and the ethical debates raised by changing our DNA have stalled progress. One such problem is the potential for CRISPR-Cas9 to trigger an immune response, resulting in toxicity. However, new...