Featured journal article: Advances in single-cell technologies in immunology


The immune system is composed of heterogeneous populations of immune cells that regulate physiological processes and protect organisms against diseases. Single-cell technologies have been used to assess immune cell responses at the single-cell level, which are crucial for identifying the causes of diseases and elucidating underlying biological mechanisms to facilitate medical therapy.

In this review, the authors discuss the most recent advances in the development of single-cell technologies to investigate cell signaling, cell–cell interactions and cell migration. Each technology’s advantages, limitations and applications in immunology are also reviewed.


Get more information on single-cell multiomic approaches in our Spotlight: Next-generation multiomics.