Integrating organ-on-a-chip

Organ-on-a-chip (OOC) technologies, also known as microphysiological systems (MPS), allow researchers to culture physiologically relevant combinations of primary human cells together in a microfluidic chip. These chips, and their ability to mimic the body’s environment, encourage the cells to form tissue or organ replicas. These in vitro organ models can then be used to test drug toxicity and efficacy, as well as for identifying druggable targets.

In this In Focus, in partnership with CN Bio, we introduce you to OOC technologies and provide a few tips for getting started with them. You can also hear more about how these OOC models differ from organoids and why they provide meaningful data for therapeutic development, among other applications.