Surface plasmon resonance

Surface plasmon resonance (SPR) technology has become an essential tool for researchers in drug discovery, protein engineering and beyond. By monitoring the real-time shift in refractive index as two biomolecules bind, researchers can determine the binding kinetics and affinity of the interaction as well as the concentration of the analyte. Its label-free and real-time nature makes it an attractive method for researchers looking to study the interactions between biomolecules, such as proteins, DNA and small molecules.

In this In Focus, in association with Sartorius (Göttingen, Germany), we provide an overview of how SPR works, how it compares to other popular techniques for measuring biomolecular interactions and how you can use SPR to further your research. Check out our animated video, infographic, podcast and eBook for all you need to know about SPR.