A tiny fluorescence microscope that can be mounted onto mice with 3D-printed see-through skulls has opened new avenues for neuroimaging studies. A recent study from researchers at the University of Minnesota (MN, USA), led by Suhasa Kodandaramaiah, presents a newly developed microscope that could have huge implications for holistic, long–term neuroimaging studies. Micro in every sense of the word, the 3–gram microscope allows for imaging of a mouse brain surface for almost a year at a time. Monitoring neural activity in the brain as an individual or animal completes a task or carries out a routine function is nothing new. However, these practices have been limited...
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