Rapid, low-cost detection of genomic aberrations with Flongle

Written by Oxford Nanopore

The extensive role of gene fusions in malignancies is well recognized, ranging from the characteristic BCR-ABL1 gene fusion found in breast tumors to the diverse range of FGFR2 fusions seen in certain liver cancers. Consequently, gene fusion detection is central to the diagnosis and treatment of many tumors.

Read this Case Study to learn more about how a team from Duke University Medical Center (NC, USA) has been evaluating ways to improve how fusions can be detected and assessed – making use of the Flongle and its ability to reduce costs.

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In this Case Study, find out more about:

  • Advantages and disadvantages of current sequencing methods available
  • Potential utility of the Flonge for detecting fusions
  • The result of the Flongle sequencing pipeline in terms of detecting fusions

And much more!

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