Introducing single-cell sequencing

Single-cell sequencing has swept genomics and transcriptomics space, allowing researchers to delve deeper into cell properties like gene expression than previous methods that simply provided ensemble average measurements of all the cells in a sample. The technique has has such an impact that it has been recognized as Nature’s Method of the Year twice in one decade; it was first awarded for its initial development in 2013 and then for the addition of multimodal omic capabilities in 2019.

As part of our In Focus on single-cell sequencing, this video introduces these approaches, their applications and challenges.