Become a member of BioTechniques (it's free!) and receive the latest news in the life sciences and member-exclusives.

Nanopore sequencing: how does it work?

Written by Oxford Nanopore

Oxford Nanopore  sequencing devices use flow cells that contain tiny holes – nanopores – embedded in an electro-resistant membrane. When DNA passes through a nanopore, the current is disrupted, producing a ‘squiggle’ that is specific to the particular base that has passed through in that moment. These squiggles can be decoded using basecalling algorithms to determine the DNA or RNA sequence in real time.

For more information, please visit the following resources and pages:

 

 


Submit Your Research to the F1000Research Genomics & Genetics Gateway

Advance the fields of genomics and genetics by publishing your research with the F1000Research Genomics & Genetics Gateway. With trusted publishing, open access, and transparent peer review, your work will uphold the highest standards of rigor and integrity while driving innovation in PCR, sequencing, and genetic analysis.

Join a platform that values transparency, openness, and author control. Submit your research today at F1000Research Genomics & Genetics Gateway.