An end-to-end workflow for exploring spatial biology through multiplex IHC
Analysis methods enhance our understanding of spatial biology, providing deeper insights into cellular interactions and tissue architecture.
In this webinar, we will explore the intricacies of multiplexed immunohistochemistry (IHC), a cutting-edge technique that allows for the simultaneous detection of multiple biomarkers in a single tissue section. We will also focus on how spatial analysis methods enhance our understanding of spatial biology, providing deeper insights into cellular interactions and tissue architecture. First, we will review an open-source workflow for pathologist-in-the-loop segmentation and classification. Then, we will demonstrate the practical applications of this approach across several peer-reviewed publications.
What will you learn?
Attendees will gain valuable insight into the latest technological advancements in multiplex IHC analysis, practical applications in research and clinical diagnostics, and the challenges and solutions in image analysis and interpretation.
Who this may interest?
This webinar is designed for scientists, researchers, and clinicians who are keen to expand their expertise in tissue imaging and analysis, and to explore how these technologies are shaping the future of biological and medical research.
Speakers
Danielle Fails
Spatial Biology Manager
Bethyl Laboratories, Fortis Life Sciences (TX, USA)
Danielle Fails received her graduate degree in biology from Sam Houston State University (TX, USA) conducting histological research on invasive lionfish. She then began her career at MD Anderson Cancer Center’s Department of Veterinary Medicine and Surgery (TX, USA), later serving as manager of Dr. Yejing Ge’s skin cancer research lab. Currently, she serves as Spatial Biology Manager of Bethyl Laboratories where her team’s primary focus is on development, optimization, and imaging of multiplex immunofluorescent projects. When she’s not diving into the latest antibodies or fostering collaborative research, Fails enjoys baking treats for her coworkers and playing board games with her two daughters.
Mark Zaidi
President and Founder
Pathomics.io (Toronto, Canada)
Mark Zaidi, an honors graduate in biology from Toronto Metropolitan University, is enhancing digital pathology with pathologist-in-the-loop methodologies. As a doctoral candidate in medical biophysics at the University of Toronto, Zaidi has earned 11 awards and scholarships for his work in spatial analysis of highly multiplexed images. His research, which includes over 330 citations in nine peer-reviewed publications, spans diverse areas from cancer immunotherapy to kidney transplant rejection variability. Co-founding Pathomics.io with Trevor McKee, Zaidi leads the offering of personalized analysis solutions for multiplexed images in this innovative contract research organization.
Looking for more spatial biology resources? Check out Fortis Life Sciences’ In Focus!
In association with
This webinar was recorded on Tuesday 5 March 2024