Spatial biology: the importance of quality antibodies
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Spatial biology is an emerging interdisciplinary field that seeks to understand the intricate relationships between cellular components and their spatial organization within tissues and organs. Protein methodologies such as multiplex immunofluorescence or imaging mass cytometry use antibodies to label cells within the tissue microenvironment. In order to produce quality results, these techniques rely on highly validated antibodies to produce data that improves our biological understanding of cancer and other diseases. Here we describe validated panels for studying the immune contexture in the tissue microenvironment using two cutting-edge platforms, the Akoya PhenoImager™ HT and the Lunaphore COMET™.
What will you learn?
- Techniques for multiplex imaging, including cyclic IF and tyramide signal amplification
- Applications of multiplex imaging in cancer, immunology and cardiovascular research
- Technical considerations, challenges and best practices for high-plex imaging
- The multiplex imaging and histology capabilities offered by Fortis as a CRO service
Who may this interest?
- Academic & industry scientists interested in the value of high-plex advanced imaging techniques
- Preclinical scientists in cancer biology, molecular biology, cell biology, immunology, biochemistry and other related fields
Speaker
Mike Spencer
Senior Director of Antibody Validation and Immunohistochemistry
Bethyl Laboratories (TX, USA)
Mike Spencer is the Senior Director of Antibody Validation and Immunohistochemsitry at Fortis Life Sciences. He received his doctorate in Molecular and Cellular Biochemistry from the University of Kentucky (KY, USA). The immunohistochemistry lab at Fortis Life Sciences validates the performance of new antibody products in immunohistochemistry and immunocytochemistry applications. Mike has been integral in extending the capabilities of the immunochemistry lab to include multiplex immunoassays for spatial biology.
In association with
This webinar was recorded on June 29th 2023