Modeling evolutionary history with ‘Neanderthalized’ brain organoids

Written by Tristan Free (Digital Editor)

Brain Organoids Neanderthal evolution

New organoid methods coupled with genomic studies have allowed for the creation of Neanderthalized brain organoids for the study of evolutionary history. As a species, we are fascinated by what makes us special. The desire to identify what makes us unique on an individual level is perhaps reflected in our drive to understand why Homo sapiens have flourished, while other hominids have become extinct. However, the ability to fully explore what separates us from our closest extinct relatives, Denisovans and Neanderthals, has been hampered by the lack of a physical record of their brains – until now. The significant size...

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