Recombinant adeno-associated virus (AAV) is a commonly used vector in gene therapy. The production of AAV requires advanced analytical techniques to ensure the final product is efficacious. In this infographic, we explore how high-performance liquid chromatography (HPLC) is used as an analytical tool in the production of AAV-based gene therapies, including top tips for using the technique to achieve better quantification, greater purity and optimized processes.
- How HPLC and HPLC-MS are utilized in the production of AAV-based gene therapies
- The importance of developing standardized analytical techniques throughout AAV development and manufacturing
- Tips on achieving better quantification, greater purity and optimized processes