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Exercise, lactate and depression: what’s the link?

Written by Tristan Free (Digital Editor)

Synpases linking lactate and depression

Researchers have revealed aspects of the mechanism linking exercise, lactate and depression, bringing the field closer to more effective therapeutics for the condition. To many, lactate likely triggers thoughts of its precursor, lactic acid, and the searing muscle cramps that it can induce after strenuous exercise. However, in recent years, the impact of lactate has been increasingly linked to the commonly observed mental health benefits that accompany physical exercise. With more attention being drawn to mental health disorders – the WHO lists depression as the leading cause of disability worldwide – and current treatments proving effective for roughly 30% of...

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