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The spatial methods that expose how tumors evade the immune system

Written by Beatrice Bowlby (Assistant Editor)

In this interview with Brian Brown (left), molecular biologist and immunologist at the Icahn School of Medicine at Mount Sinai (NY, USA) and director of the Genomics Institute, he tells us about how he uses spatial methods to research the genes responsible for cancers’ evasion of the immune system and how this informs the development of immunotherapies that can be used to treat cancer. The immune system can recognize harmful agents like viruses and even tumors, but cancers develop ways to keep the immune system from wiping them out. Many patients don’t respond to current immunotherapy drugs and that is...

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