Become a member of BioTechniques (it's free!) and receive the latest news in the life sciences, member-exclusives and 10% off BioTechniques article processing fees

Application Note: spatially-resolved heterogeneity of triple-negative breast cancer

Written by 10x Genomics
Cancer research Cell and tissue biology Immunology Whole-genome studies

This Application Note by 10x Genomics illustrates how the integration of spatial and single nuclei gene expression data can better characterize triple-negative breast cancer by resolving intratumoral heterogeneity, defining the extent of immune infiltration, and localizing specific cell types and states.

Download Application NoteMore information

This Application Note highlights:

  • The characterization of intratumoral heterogeneity within pathologist-annotated invasive carcinoma
  • The integration of spatial and single cell gene expression data to visualize localized enrichment of specific cell subtypes and states
  • The refinement of immune-cell boundaries and immune cell-type composition

… And much more!

This content was provided by 10x Genomics.