eBook: Antibody discovery, validation and process optimization
Antibodies are widely used throughout the life sciences, commonly for western blotting, flow cytometry, ELISAs and immunohistochemistry, among other life science techniques. They are also a popular option for therapeutic development. There are numerous steps that must be taken to identify an antibody for therapeutic use and to validate its efficacy against the disease of interest. The processes can be lengthy, costly and challenging; therefore, there is a need for novel tools to accelerate antibody discovery and development timelines.
This eBook, sponsored by Telesis Bio, highlights the importance of antibody discovery for both basic research and therapeutic purposes, focusing particularly on identifying quality research antibodies, optimizing their development and exploring their potential for therapeutic use.
Introduction
Interview: Developing immunodiagnostics to tackle antimicrobial resistance
Expert Opinion: An approach to identifying quality research antibodies
White Paper: Rethinking lead optimization: adopting new synthetic biology tools to accelerate development timelines
Technology News: Profiling a human: the role of antibodies
Review: Antibody validation for protein expression on tissue slides: a protocol for immunohistochemistry
Methodology: Bioanalysis of therapeutic monoclonal antibody by peptide adsorption-controlled LC–MS