Accelerating antibody discovery using advanced flow cytometry
The past decade has seen an explosion in the number of antibody-based therapeutics on the market. A huge driver of this has been the advancement of technologies that improve the time and efficiency of antibody discovery. Robust, high-throughput techniques for screening antibody libraries have led to better quality hits in less time. Moreover, combining several in vitro methods to assess a broad range of antibody parameters, for example target binding and Fc function characteristics, builds a full profile of a candidate molecule and informs preclinical studies.
What will you learn?
- The use of advanced flow cytometry to assess antibody-cell interactions, in the context of live-cell antibody binding, antibody competition and antibody internalization
- How the high-throughput iQue® Advanced Flow Cytometry Platform can speed up antibody screening
- Fc functional characterization of monoclonal antibodies using the iQue® with associated phenotype and function kits
Who may this interest?
- Immunologists
- Immuno-oncology
- Virology researchers
- Neuroscientists and cancer immunotherapy drug discovery researchers
- In biotechnology
- Pharmaceuticals
- Biopharma
- Research institutes
- Core facility and academia
Speaker
Kirsty McBain
Scientist
Analytics, Sartorius
Kirsty McBain is a Scientist in the BioAnalytics Group of Sartorius, where she is involved in the research and development of novel applications.
Kirsty’s efforts are focused on the iQue® Advanced Flow Cytometry Platform, where she has supported a number of the immuno-oncology campaigns that are used to exemplify how Sartorius technology can be applied to the drug discovery process.
Kirsty obtained a master’s degree in Biochemistry at the University of Bristol (UK) before joining Sartorius in 2019.
This webinar was recorded on Wednesday 15 March 2023.
