Resolving brain architecture with comprehensive spatial gene expression

Spatially resolved gene expression can provide a powerful complement to traditional histopathology methods, enabling a greater understanding of cellular heterogeneity and organization within the central nervous system. This Data Spotlight explores how integrated sequencing and histological data from the Visium Spatial Gene Expression assay enabled unbiased clustering of cell types that reliably correlates with the neuroanatomy of both rodent and human specimens.