Cell line development
Cell line development is a crucial step in the drug discovery and development pipeline. It is essential in the manufacturing of biologics, as well as for drug screening, disease modeling and studying gene function, yet it is plagued by several well-documented challenges that can significantly impact confidence in results, overall timelines and regulatory approvals.
Initial monoclonality verification and subsequent growth and productivity assessments are required before potential clone candidates can be selected for further characterization. However, many sub-optimal clones may be chosen during these early stages of the cell line development workflow.
This spotlight will explore:
- The role of cell line development in drug discovery and biotherapeutic production
- Common challenges faced during cell line development
- How cell selection technologies can help overcome these obstacles and streamline cell line development
This feature was sponsored by Sartorius.
