Infographic: Technologies for detecting intact DNA methylation

Written by Oxford Nanopore

DNA methylation oxford nanopore in focus

DNA methylation is implicated in normal, fundamental biological processes, such as development and aging; as well as disease states like cancer, neurological disorders and autoimmunity. Traditional methods for detection of DNA methylation require steps that can damage DNA. Novel methods can directly detect DNA methylation from the original DNA strand, without damage, and afford many additional benefits.

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  • Genome-wide methylation calling approaches
  • Challenges that can arise with traditional DNA methylation detection
  • Benefits of novel nanopore sequencing technologies for DNA methylation detection